Space Marine, an over-the-shoulder worked really well with a controller, but high levels of online play were pretty much mouse/keyboard. Twitch shots with lascannons, fine mid-air control and combat with the assault jump packs, etc. Melee is about the only time gamepads offered a greater degree of control (thumbstick vs 8-directional).
@rthicki ahh, makes sense
@rthicki ahh, makes sense